Del(15Rr357-Rr303293)2Jta
Targeted Allele Detail

Summary

• Symbol: Del(15Rr357-Rr303293)2Jta
• Name: deletion, Chr 15, Jussi Taipale 2
• MGI ID: MGI:7434631
• Synonyms: Myc^delta2-540
• Gene: Del(15Rr357-Rr303293)2Jta Location: unknown Genetic Position: Chr15, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:257088
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Modified regulatory region)
• Mutations: Insertion, Intergenic deletion
• Del(15Rr357-Rr303293)2Jta involves 12 genes/genome features (Rr357, Gm62908, Gm49498 ...) View all
• Mutation details: An ~538 kb region, containing Myc enhancers Rr357, Rr21 and Rr356 and the 5' end of CTCF-binding region Rr303293, was deleted by cre-mediated inter-allelic recombination between the loxP sites in alleles Rr357^tm1.1Jta and Rr303293^tm1.1Jta. (J:257088)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(15Rr357-Rr303293)2Jta Mutation: 0 strains or lines available

References

• Original: J:257088 Dave K, et al., Mice deficient of Myc super-enhancer region reveal differential control mechanism between normal and pathological growth. Elife. 2017 Jun 6;6:e23382
• All: 2 reference(s)