Rnf39^em1Zwei
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rnf39^em1Zwei
• Name: ring finger protein 39; endonuclease-mediated mutation 1, Wei Zhao
• MGI ID: MGI:8210419
• Gene: Rnf39 Location: Chr17:37253943-37258878 bp, + strand Genetic Position: Chr17, 19.16 cM
• Alliance: Rnf39^em1Zwei page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/cas9 mediated recombination using guide RNAs created a deletion encompassing exon 1. (J:357975)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnf39 Mutation: 20 strains or lines available

References

• Original: J:357975 Wang W, et al., RNF39 mediates K48-linked ubiquitination of DDX3X and inhibits RLR-dependent antiviral immunity. Sci Adv. 2021 Mar;7(10)
• All: 2 reference(s)