About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rnf39em1Zwei
endonuclease-mediated mutation 1, Wei Zhao
MGI:8210419
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rnf39em1Zwei/Rnf39em1Zwei involves: C57BL/6 MGI:8210422


Genotype
MGI:8210422
hm1
Allelic
Composition		 Rnf39em1Zwei/Rnf39em1Zwei
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rnf39em1Zwei mutation (0 available); any Rnf39 mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

immune system
increased interferon-beta secretion ( J:357975 )
• enhanced SeV- and VSV-induced secretion
increased interleukin-6 secretion ( J:357975 )
• enhanced SeV- and VSV-induced secretion
decreased susceptibility to Riboviria infection ( J:357975 )
• replication of vesicular stomatitis virus is attenuated and viral burden is reduced in the lung and spleen of infected mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory