Cd163^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Cd163^{tm1(KOMP)Vlcg}
• Name: CD163 antigen; targeted mutation 1, Velocigene
• MGI ID: MGI:3799792
• Synonyms: CD163^-, Cd163^tm1Vlcg
• Gene: Cd163 Location: Chr6:124281615-124307486 bp, + strand Genetic Position: Chr6, 59.13 cM, cytoband F2
• Alliance: Cd163^{tm1(KOMP)Vlcg} page
• IMPC: Cd163 gene page

Mutation origin

• Mutant Cell Lines: 10143B-A3, 10143B-F4, 10143C-F11, 10143E-B5, 10143F-B6, 10143F-E2
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 24636bp between positions 124281697-124306332 of Chromosome 6 (Build GRCm39). (J:136110)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Cd163 Mutation: 71 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 9 reference(s)