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Ncr1tm1.1(icre)Viv
Targeted Allele Detail
Summary
Symbol: Ncr1tm1.1(icre)Viv
Name: natural cytotoxicity triggering receptor 1; targeted mutation 1.1, Eric Vivier
MGI ID: MGI:5308410
Synonyms: Cd335Cre, NKp46-cre, Nkp46iCre, NKp46-iCre
Gene: Ncr1  Location: Chr7:4340723-4348163 bp, + strand  Genetic Position: Chr7, 2.5 cM
Alliance: Ncr1tm1.1(icre)Viv page
Generation of Ncr1tm1.1(icre)Viv.

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:180265
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Ncr1tm1.1(icre)Viv expression driven by 1 gene
 
Mutation detailsAn IRES-icre-Frt-neo-Frt cassette was inserted at the 3' end of the Ncr1 (Nkp46) gene by homologous recombination. The resulting mice were crossed to an Flp expressing strain to excise the neo resistance cassette. (J:180265)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ncr1 (mouse)
Summary of all recombinase alleles driven by Ncr1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ncr1 Mutation:  39 strains or lines available
References
Original:  J:180265 Narni-Mancinelli E, et al., Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptor. Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18324-9
All:  110 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/02/2024
MGI 6.13
The Jackson Laboratory