Tg(CAG-PLA2G3)#aMurm
Transgene Detail

Summary

• Symbol: Tg(CAG-PLA2G3)#aMurm
• Name: transgene insertion #a, Makoto Murakami
• MGI ID: MGI:5517570
• Synonyms: PLA2G3^tg
• Transgene: Tg(CAG-PLA2G3)#aMurm Location: unknown
• Alliance: Tg(CAG-PLA2G3)#aMurm page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-PLA2G3)#aMurm expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  PLA2G3 (50487)

  Pla2g3

  (MGI:2444945)

• Mutation details: The transgene contains a CAG promoter driving ubiquitous expression of the human cDNA. Cre-mediated recombination removed a floxed neomycin resistance cassette inserted between the promoter and cDNA. The pound symbol (#) is used when no line is specified and/or lines are pooled. The #a line reflects the cre-recombined transgene while the unrecombined transgene is referred to as line #. (J:143385)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:143385 Sato H, et al., Analyses of group III secreted phospholipase A2 transgenic mice reveal potential participation of this enzyme in plasma lipoprotein modification, macrophage foam cell formation, and atherosclerosis. J Biol Chem. 2008 Nov 28;283(48):33483-97
• All: 2 reference(s)