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Del(16Dgcr2-Hira)1Rak
Targeted Allele Detail
Summary
Symbol: Del(16Dgcr2-Hira)1Rak
Name: deletion, Chr 16, Raju Kucherlapati 1
MGI ID: MGI:3702642
Synonyms: Del1Rak, Lgdel
Gene: Del(16Dgcr2-Hira)1Rak  Location: Chr16:17658219-18789059 bp  Genetic Position: Chr16, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:67796
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129S6/SvEvTac and STOCK 129/Sv and C57BL/6J and SJL
Mutation
description
Allele Type:    Targeted
Mutations:    Intergenic deletion, Intragenic deletion
  Del(16Dgcr2-Hira)1Rak involves 51 genes/genome features (Gm15954, Gm26170, Gm26219 ...) View all
 
Mutation detailsMutant mice containing loxP sites inserted into the Dgcr2tm1Ais and Hiratm2Pjs loci were crossed with mice expressing cre in the germline to remove the floxed region between the loci. This deletion encompasses 24 genes. (J:67796)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 18 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Del(16Dgcr2-Hira)1Rak Mutation:  0 strains or lines available
References
Original:  J:67796 Merscher S, et al., TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome. Cell. 2001 Feb 23;104(4):619-29
All:  23 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory