Gm20518 Gene Detail

Summary

• Symbol
  Gm20518
• Name
  predicted gene 20518

• Feature Type
  protein coding gene
• IDs
  MGI:5141983
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr16:17653141-17709535 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 16, 11.05 cM

Strain
Comparison

• SNPs within 2kb
  230 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5141983	protein coding gene	Chr16:17653141-17709535 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0022593	protein coding gene	Chr16:15017837-15078547 (-)
A/J	MGP_AJ_G0022554	protein coding gene	Chr16:14270554-14327357 (-)
AKR/J	MGP_AKRJ_G0022531	protein coding gene	Chr16:14826088-14887032 (-)
BALB/cJ	MGP_BALBcJ_G0022557	protein coding gene	Chr16:14422420-14480481 (-)
C3H/HeJ	MGP_C3HHeJ_G0022324	protein coding gene	Chr16:14975421-15033614 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0023008	protein coding gene	Chr16:15252133-15320797 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0020528	protein coding gene	Chr16:14330179-14385876 (-)
CAST/EiJ	MGP_CASTEiJ_G0021852	protein coding gene	Chr16:14894833-14950140 (-)
CBA/J	MGP_CBAJ_G0022295	protein coding gene	Chr16:15929516-15994191 (-)
DBA/2J	MGP_DBA2J_G0022425	protein coding gene	Chr16:14183783-14239671 (-)
FVB/NJ	MGP_FVBNJ_G0022401	protein coding gene	Chr16:14231696-14289654 (-)
LP/J	MGP_LPJ_G0022492	protein coding gene	Chr16:14793723-14861963 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0022422	protein coding gene	Chr16:15616071-15673112 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0023019	protein coding gene	Chr16:14772249-14832422 (-)
PWK/PhJ	MGP_PWKPhJ_G0021595	protein coding gene	Chr16:14443678-14498456 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0021423	protein coding gene	Chr16:14743342-14801736 (-)
WSB/EiJ	MGP_WSBEiJ_G0021899	protein coding gene	Chr16:14760104-14816796 (-)

Homology

• Gene Tree
  Gm20518
  

Human Diseases

• References
  3 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  45 phenotype references
  

• All Mutations and Alleles
  7
• Endonuclease-mediated
  2
• Targeted
  5
• Genomic Mutations
  7 involving Gm20518
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  7 strains or lines available

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  22
• UniProt
  1

• Ensembl
  ENSMUSG00000092470 (Evidence)

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000092470	Ensembl Gene Model | MGI Sequence Detail	56395	C57BL/6J
transcript	ENSMUST00000150068	Ensembl | MGI Sequence Detail	3811	Not Applicable
polypeptide	ENSMUSP00000115071	Ensembl | MGI Sequence Detail	580	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR016187 C-type lectin fold
  IPR001304 C-type lectin-like
  IPR016186 C-type lectin-like/link domain superfamily
  IPR034010 DGCR2-like, C-type lectin-like domain
  IPR042378 Integral membrane protein DGCR2/IDD
  IPR036055 LDL receptor-like superfamily
  IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved site
  IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
  IPR001007 VWFC domain

References

• Summaries
  All 48

  Diseases 3

  Phenotypes 45
• Earliest
  J:58432 Kimber WL, et al., Deletion of 150 kb in the minimal DiGeorge/velocardiofacial syndrome critical region in mouse. Hum Mol Genet. 1999 Nov;8(12):2229-37
• Latest
  J:342597 Rummell BP, et al., Altered corollary discharge signaling in the auditory cortex of a mouse model of schizophrenia predisposition. Nat Commun. 2023 Nov 15;14(1):7388

TSS for Gm20518:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr140215	Chr16:17709502-17709564 (-)	2 bp
Tssr140214	Chr16:17690487-17690529 (-)	19,027 bp