Phex^Hyp-Duk
Spontaneous Allele Detail

Summary

• Symbol: Phex^Hyp-Duk
• Name: phosphate regulating endopeptidase homolog, X-linked; hypophosphatemia, Duke
• MGI ID: MGI:2388890
• Gene: Phex Location: ChrX:155945071-156198282 bp, - strand Genetic Position: ChrX, 72.38 cM
• Alliance: Phex^Hyp-Duk page

Phex^Hyp-Duk/Y with littermate ⁺/Y control

Show the 4 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: CAnBomUrd.Cg-Foxn1^nu

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: Genomic PCR and Southern blot analysis indicated a deletion of at least 30 kb containing exons 13 and 14 of the Phex gene.
• Inheritance: Semidominant

Disease models

Expression

In Structures Affected by this Mutation:

23 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Phex Mutation: 21 strains or lines available

References

• Original: J:88352 Lorenz-Depiereux B, et al., New intragenic deletions in the Phex gene clarify X-linked hypophosphatemia-related abnormalities in mice. Mamm Genome. 2004 Mar;15(3):151-61
• All: 4 reference(s)