Cemip2^tm1.1Cya
Targeted Allele Detail

Summary

• Symbol: Cemip2^tm1.1Cya
• Name: cell migration inducing hyaluronidase 2; targeted mutation 1.1, Cyagen Biosciences
• MGI ID: MGI:6854703
• Synonyms: Cemip2^tm1.1Cgen, Tmem2^flox
• Gene: Cemip2 Location: Chr19:21755706-21835724 bp, + strand Genetic Position: Chr19, 15.54 cM
• Alliance: Cemip2^tm1.1Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:317425
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 4 and 5 were floxed and an FRT flanked selection cassette was inserted via homologous recombination. Flp mediated recombination removed the selection cassette. (J:317425)

Expression

In Mice Carrying this Mutation:	13 assay results
In Structures Affected by this Mutation:	7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cemip2 Mutation: 93 strains or lines available

References

• Original: J:317425 Tobisawa Y, et al., The cell surface hyaluronidase TMEM2 is essential for systemic hyaluronan catabolism and turnover. J Biol Chem. 2021 Oct 6;297(5):101281
• All: 3 reference(s)