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Tg(Cd8a*-cre)B8Asin
Transgene Detail
Summary
Symbol: Tg(Cd8a*-cre)B8Asin
Name: transgene insertion B8, Alfred Singer
MGI ID: MGI:4462361
Synonyms: E8III-Cre
Transgene: Tg(Cd8a*-cre)B8Asin  Location: unknown  
Alliance: Tg(Cd8a*-cre)B8Asin page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Cd8a*-cre)B8Asin expression driven by 1 gene
 
Mutation detailsA transgene was constructed with the E8III enhancer and promoter elements from Cd8a driving expression of cre recombinase in SP and DP thymocytes. (J:158504)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cd8a (species not specified)
Summary of all recombinase alleles driven by Cd8a.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:158504 Park JH, et al., Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells. Nat Immunol. 2010 Mar;11(3):257-64
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/02/2024
MGI 6.13
The Jackson Laboratory