Hspa9^{Gt(IST14901H6)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Hspa9^{Gt(IST14901H6)Tigm}
• Name: heat shock protein 9; gene trap IST14901H6, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:5265211
• Gene: Hspa9 Location: Chr18:35070467-35087404 bp, - strand Genetic Position: Chr18, 18.8 cM, cytoband C
• Alliance: Hspa9^{Gt(IST14901H6)Tigm} page

Mutation origin

• Mutant Cell Line: IST14901H6
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: Lex3.13 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: A gene trap cassette inserted in intron 3 of the locus. Heterozygous mutant mice show a 50% reduction in the encoded protein in bone marrow and spleen lysates compared to controls. RT-PCR expression analysis of the transcript in bone marrow extracts also showed a 50% reduction in transcript levels in heterozyogotes. (J:227164)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  IST14901H6HMR1	JM379917 ; (MGI Seq Detail)	inverse PCR	Chr18:35085135-35085361 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  53 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Hspa9 Mutation: 48 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)