Zbtb1^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Zbtb1^m2Btlr
• Name: zinc finger and BTB domain containing 1; mutation 2, Bruce Beutler
• MGI ID: MGI:6286068
• Synonyms: old_friend
• Gene: Zbtb1 Location: Chr12:76417040-76443724 bp, + strand Genetic Position: Chr12, 33.73 cM
• Alliance: Zbtb1^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to T transition at base pair 76,385,891 (v38) on chromosome 12, or base pair 15,700 in the GenBank genomic region NC_000078. The mutation corresponds to residue 877 in the mRNA sequence NM_178666 within exon 2 of 2 total exons. The mutation results in an threonine to isoleucine substitution at position 217 (T217I) in the ZBTB1 protein. (J:272845)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zbtb1 Mutation: 115 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3694

References

• Original: J:272845 Zhong X, et al., Mutagenetix entry for old_friend. MGI Direct Data Submission. 2019
• All: 1 reference(s)