Spag11a^em2Mgef
Endonuclease-mediated Allele Detail

Summary

• Symbol: Spag11a^em2Mgef
• Name: sperm associated antigen 11A; endonuclease-mediated mutation 2, Mouse Genome Engineering Facility
• MGI ID: MGI:8190590
• Gene: Spag11a Location: Chr8:19207902-19209594 bp, + strand Genetic Position: Chr8, 10.35 cM
• Alliance: Spag11a^em2Mgef page

Mutation origin

• Strain of Origin: C57BL/6NJNcbs

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting generated a 291-bp deletion (nucleotides between 712 and 1002) which includes most of exon 1 and part of intron 1. (J:363226)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Spag11a Mutation: 6 strains or lines available

References

• Original: J:363226 Aisha J, et al., Effect of Spag11a gene knockout on the epididymis in mice: A histopathological and molecular analyses. Cell Biochem Funct. 2024 Jul;42(5):e4096
• All: 2 reference(s)