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Tg(Tie1-cre)9Ref
Transgene Detail
Summary
Symbol: Tg(Tie1-cre)9Ref
Name: transgene insertion 9, Reinhard Fassler
MGI ID: MGI:2385916
Synonyms: Tie-1-Cre, Tie1-Cre
Transgene: Tg(Tie1-cre)9Ref  Location: unknown  
Alliance: Tg(Tie1-cre)9Ref page
Transgene
origin
Germline Transmission:  Earliest citation of germline transmission: J:67916
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Tie1-cre)9Ref expression driven by 1 gene
 
Mutation detailsThe transgene is composed of a 1.15 kb fragment of mouse Tie1 promoter fused to the cre recombinase gene and a nuclear localization signal, and a separate floxed PGK-neo cassette. The mouse Tie1 promoter directs expression of the cre transgene in endothelial cells. (J:67916)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tie1 (mouse)
Summary of all recombinase alleles driven by Tie1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:67916 Gustafsson E, et al., Tie-1-directed expression of Cre recombinase in endothelial cells of embryoid bodies and transgenic mice. J Cell Sci. 2001 Feb;114(Pt 4):671-6
All:  50 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory