Gnai2tm2.1Lbi
Targeted Allele Detail
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Symbol: |
Gnai2tm2.1Lbi |
Name: |
G protein subunit alpha i2; targeted mutation 2.1, Lutz Birnbaumer |
MGI ID: |
MGI:5471645 |
Synonyms: |
Galphai2flx, Gnai2flx |
Gene: |
Gnai2 Location: Chr9:107491324-107512542 bp, - strand Genetic Position: Chr9, 58.43 cM
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Alliance: |
Gnai2tm2.1Lbi page
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Rib fusion phenotype is enhanced in Gnai3tm1Lbi/Gnai3tm1Lbi mice by loss of Gnai2 in cartilage
Show the 1 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:194587
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129S/SvEv
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 2 and a floxed pgk-neo cassette was inserted downstream of exon 4 via homologous recombination. Cre mediated recombination removed the neo cassette.
(J:194587)
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Generation of the Gnai2tm2.1Lbi allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gnai2 Mutation: |
54 strains or lines available
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Original: |
J:194587 Ustyugova IV, et al., IEX-1 deficiency protects against colonic cancer. Mol Cancer Res. 2012 Jun;10(6):760-7 |
All: |
15 reference(s) |
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