Tg(SV40-NRAS*G12D)1Sco Transgene Detail MGI Mouse (MGI:3757990)

Tg(SV40-NRAS*G12D)1Sco
Transgene Detail

Summary

Symbol:	Tg(SV40-NRAS*G12D)1Sco
Name:	transgene insertion 1, Suzanne Cory
MGI ID:	MGI:3757990
Synonyms:	Emu-N-ras
Transgene:	Tg(SV40-NRAS*G12D)1Sco Location: unknown
Alliance:	Tg(SV40-NRAS*G12D)1Sco page

Transgene
origin

Strain of Origin:

Transgene
description

Transgene Type:		Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:		Insertion
		Mutation details: The SV40 early region promoter with the immunoglobulin heavy chain enhancer (Emu) was fused to a human NRAS open reading frame carrying a G12D point mutation. (J:125150)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Tumor Data

List all tumor models in MMHCdb carrying Tg(SV40-NRAS*G12D)1Sco

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

Original:	J:125150 Harris AW, et al., Transgenic mouse models for hematopoietic tumorigenesis. Curr Top Microbiol Immunol. 1988;141:82-93
All:	3 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23