Sbsn^em1Ham
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sbsn^em1Ham
• Name: suprabasin; endonuclease-mediated mutation 1, Hamamatsu University School of Medicine
• MGI ID: MGI:6500980
• Gene: Sbsn Location: Chr7:30450896-30455559 bp, + strand Genetic Position: Chr7, 19.24 cM
• Alliance: Sbsn^em1Ham page

Mutation origin

• Strain of Origin: C57BL/6NCrl

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 1 deleted a single nucleotide (c.57delA). (J:296400)
• Inheritance: Not Specified

Expression

In Mice Carrying this Mutation:	12 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sbsn Mutation: 27 strains or lines available

References

• Original: J:296400 Nakazawa S, et al., Suprabasin-null mice retain skin barrier function and show high contact hypersensitivity to nickel upon oral nickel loading. Sci Rep. 2020 Sep 3;10(1):14559
• All: 1 reference(s)