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Targeted Allele Detail
Symbol: Pip5k1btm1Tssk
Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 beta; targeted mutation 1, Takehiko Sasaki
MGI ID: MGI:3577649
Synonyms: PIPKIalpha-
Gene: Pip5k1b  Location: Chr19:24272158-24533236 bp, - strand  Genetic Position: Chr19, 19.44 cM, cytoband C1
Alliance: Pip5k1btm1Tssk page
Germline Transmission:  Earliest citation of germline transmission: J:97991
Parent Cell Line:  E14K (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA PGK-neo replaced a 1.7 kb sequence including exon 3, the region encoding amino acids 68-106. Western blot of BMMCs confirmed absence of protein from the targeted region. (J:97991)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pip5k1b Mutation:  27 strains or lines available
Original:  J:97991 Sasaki J, et al., Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I {alpha}. J Exp Med. 2005 Mar 21;201(6):859-70
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory