Gata3^tm1.1Mbu
Targeted Allele Detail

Summary

• Symbol: Gata3^tm1.1Mbu
• Name: GATA binding protein 3; targeted mutation 1.1, Meinrad Busslinger
• MGI ID: MGI:3719568
• Synonyms: Gata3^F, Gata3^tm1.1Bchd
• Gene: Gata3 Location: Chr2:9861889-9894845 bp, - strand Genetic Position: Chr2, 6.69 cM
• Alliance: Gata3^tm1.1Mbu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:123631
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Expression of FRT recombinase resulted in the removal of the stop-IRES-GFP-neo cassette. (J:123631)

Expression

In Mice Carrying this Mutation:

8 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gata3 Mutation: 31 strains or lines available

References

• Original: J:123631 Amsen D, et al., Direct regulation of gata3 expression determines the T helper differentiation potential of notch. Immunity. 2007 Jul;27(1):89-99
• All: 21 reference(s)