Tg(HLA-B)22Hpl
Transgene Detail

Summary

• Symbol: Tg(HLA-B)22Hpl
• Name: transgene insertion 22, Hidde Ploegh
• MGI ID: MGI:2159100
• Synonyms: HLA-B27, HLA-B27.2
• Transgene: Tg(HLA-B)22Hpl Location: unknown
• Alliance: Tg(HLA-B)22Hpl page

Transgene origin

• Strain of Origin: (CBA x C57BL/LiA)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A transgene containing the human HLA-B allele, HLA-B27, was shown to be expressed in spleen cells of mice carrying the transgene. (J:74416)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:74416 Krimpenfort P, et al., Crosses of two independently derived transgenic mice demonstrate functional complementation of the genes encoding heavy (HLA-B27) and light (beta 2-microglobulin) chains of HLA class I antigens. EMBO J. 1987 Jun;6(6):1673-6
• All: 6 reference(s)