Gt(ROSA)26Sor^{tm1(B4galt1)Clib}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(B4galt1)Clib}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Claude Libert
• MGI ID: MGI:5582802
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(B4galt1)Clib} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:209737
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(B4galt1)Clib} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	B4galt1 (MGI:95705)

• Mutation details: The targeting construct introduced into the locus a splice acceptor, floxed neomycin resistance cassette with 3 polyadenylation sequences (STOP), the mouse cDNA and an IRES-EGFP. (J:209737)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 942 strains or lines available

References

• Original: J:209737 Vanhooren V, et al., Mice overexpressing beta-1,4-Galactosyltransferase I are resistant to TNF-induced inflammation and DSS-induced colitis. PLoS One. 2013;8(12):e79883
• All: 1 reference(s)