Sell^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Sell^m1Btlr
• Name: selectin, lymphocyte; mutation 1, Bruce Beutler
• MGI ID: MGI:5615716
• Synonyms: dim_sum
• Gene: Sell Location: Chr1:163889556-163908354 bp, + strand Genetic Position: Chr1, 71.37 cM
• Alliance: Sell^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to A transversion at base pair 164,066,201 (v38) on chromosome 1, or base pair 4,389 in the GenBank genomic region NC_000067. The mutation affects a thymine base 9 nucleotides from exon 4 (out of 9 total exons). The affect of the mutation on expression and localization has not been examined. The mutation is predicted to affect the splice acceptor site of intron 3, resulting in skipping of the 108-base pair exon 4 (encoding amino acids 158-193). Splicing of exon 3 to exon 5 does not generate a frame-shift. (J:217794)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sell Mutation: 41 strains or lines available

References

• Original: J:217794 Zeng M, et al., Mutagenetix entry for dim_sum. MGI Direct Data Submission. 2015
• All: 1 reference(s)