Nudt21^tm1.1Ejwpj
Targeted Allele Detail

Summary

• Symbol: Nudt21^tm1.1Ejwpj
• Name: nudix hydrolase 21; targeted mutation 1.1, Eric Wagner
• MGI ID: MGI:6385854
• Synonyms: CFIm25^f
• Gene: Nudt21 Location: Chr8:94746031-94763667 bp, - strand Genetic Position: Chr8, 46.05 cM
• Alliance: Nudt21^tm1.1Ejwpj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:283035
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 2 and 3 were floxed. Flp-mediated recombination removed the selection cassette. (J:283035)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nudt21 Mutation: 28 strains or lines available

References

• Original: J:283035 Weng T, et al., Cleavage factor 25 deregulation contributes to pulmonary fibrosis through alternative polyadenylation. J Clin Invest. 2019 May 1;129(5):1984-1999
• All: 3 reference(s)