Adgre1^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Adgre1^m2Btlr
• Name: adhesion G protein-coupled receptor E1; mutation 2, Bruce Beutler
• MGI ID: MGI:5478734
• Synonyms: onion
• Gene: Adgre1 Location: Chr17:57665691-57790527 bp, + strand Genetic Position: Chr17, 29.8 cM
• Alliance: Adgre1^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: Capillary sequencing confirmed a T to A transversion at 57542264 bp on Chromosome 17 (v37) in the GenBank genomic region NC_000083 encoding Emr1. The mutation corresponds to cDNA residue 497 in exon 5 of 23 total exons in transcript ENSMUST00000004850 (NM_010130.4 corresponds to this Ensembl transcript) and residue 497 in exon 5 of 22 total exons in transcript ENSMUST00000086763. The mutation results in a leucine (L) to premature stop codon substitution at residue 166, and may cause nonsense mediated decay of the transcript. (J:195410)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Adgre1 Mutation: 76 strains or lines available

References

• Original: J:195410 Beutler B, Direct Data Submission for onion. MGI Direct Data Submission. 2013
• All: 1 reference(s)