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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Adgre1m2Btlr
mutation 2, Bruce Beutler
MGI:5478734
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Adgre1m2Btlr/Adgre1m2Btlr C57BL/6J-Adgre1m2Btlr MGI:5478739


Genotype
MGI:5478739
hm1
Allelic
Composition		 Adgre1m2Btlr/Adgre1m2Btlr
Genetic
Background		 C57BL/6J-Adgre1m2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adgre1m2Btlr mutation (1 available); any Adgre1 mutation (80 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased macrophage cell number ( J:195410 )
• loss of F4/80+ macrophages in the peripheral blood
abnormal macrophage physiology ( J:195410 )
• loss of F4/80+ macrophages in the peripheral blood

hematopoietic system
decreased macrophage cell number ( J:195410 )
• loss of F4/80+ macrophages in the peripheral blood
abnormal macrophage physiology ( J:195410 )
• loss of F4/80+ macrophages in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory