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Tg(Gfap-cre)2Brn
Transgene Detail
Summary
Symbol: Tg(Gfap-cre)2Brn
Name: transgene insertion 2, Anton Berns
MGI ID: MGI:2663939
Synonyms: GFAP-Cre, GFAP/Cre, mGFAP-Cre
Transgene: Tg(Gfap-cre)2Brn  Location: unknown  
Alliance: Tg(Gfap-cre)2Brn page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Gfap-cre)2Brn expression driven by 1 gene
 
Mutation detailsTransgene expressing bacteriophage P1 Cre recombinase under control of the mouse Gfap promoter. This transgene is expressed in the developing forebrain and in the spinal ganglia and also in scattered precursor cells located in the EGL of the cerebellum. (J:61961)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gfap (mouse)
Summary of all recombinase alleles driven by Gfap.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Tumor Data
List all tumor models in MMHCdb carrying Tg(Gfap-cre)2Brn
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:61961 Marino S, et al., Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum. Genes Dev. 2000 Apr 15;14(8):994-1004
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory