Tbk1^M1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Tbk1^M1Btlr
• Name: TANK-binding kinase 1; mutation 1, Bruce Beutler
• MGI ID: MGI:5442100
• Synonyms: Pioneer
• Gene: Tbk1 Location: Chr10:121382360-121422692 bp, - strand Genetic Position: Chr10, 69.84 cM
• Alliance: Tbk1^M1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at position 277 (in exon 3 of 21 exons). The mutation causes a phenylalanine to isoleucine substitution at residue 40 (F40I). (J:188770)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tbk1 Mutation: 54 strains or lines available

References

• Original: J:188770 Shi H, et al., Direct Data Submission. MGI Direct Data Submission. 2012
• All: 1 reference(s)