Tg(CAG-p35)1Miur
Transgene Detail

Summary

• Symbol: Tg(CAG-p35)1Miur
• Name: transgene insertion 1, Masayuki Miura
• MGI ID: MGI:3762384
• Synonyms: p35, Tg(ACTB-p35)1Miur, Tg(CAG-p35)1Miur
• Transgene: Tg(CAG-p35)1Miur Location: unknown
• Alliance: Tg(CAG-p35)1Miur page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The transgene carries a floxed neo sequence, the baculovirus p35 coding sequence and a polyadenylation signal downstream of a chicken beta-actin promoter. Upon Cre-mediated excision of the loxP-neo-loxP sequence, the modified allele expresses p35 in tissues where Cre is expressed. (J:126593)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:126593 Hisahara S, et al., Targeted expression of baculovirus p35 caspase inhibitor in oligodendrocytes protects mice against autoimmune-mediated demyelination. EMBO J. 2000 Feb 1;19(3):341-8
• All: 5 reference(s)