Dusp11^{Gt(BB0198)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Dusp11^{Gt(BB0198)Wtsi}
• Name: dual specificity phosphatase 11 (RNA/RNP complex 1-interacting); gene trap BB0198, Wellcome Trust Sanger Institute
• MGI ID: MGI:3870220
• Synonyms: DUSP11 KO
• Gene: Dusp11 Location: Chr6:85919250-85938649 bp, - strand Genetic Position: Chr6, 37.54 cM
• Alliance: Dusp11^{Gt(BB0198)Wtsi} page

Mutation origin

• Mutant Cell Line: BB0198
• Germline Transmission: Earliest citation of germline transmission: J:301503
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT2lxr
• Mutation details: An insertion vector containing a splice acceptor, beta-geo (a fusion of beta-galactosidase and neomycin resistance genes), and a polyadenylation sequence was inserted into the intron between exon 1 and exon 2 of the gene. qPCR analysis confirmed the absence of mRNA expression in the peripheral blood, thymus, spleen, and lymph nodes of homozygous mutant mice. (J:301503)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  BB0198	DU635426 ; (MGI Seq Detail)	5' RACE	Chr6:85938419-85938623 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  1 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dusp11 Mutation: 18 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)