Tnfrsf14^tm1Wwhk
Targeted Allele Detail

Summary

• Symbol: Tnfrsf14^tm1Wwhk
• Name: tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator); targeted mutation 1, Wayne W Hancock
• MGI ID: MGI:3702279
• Synonyms: HVEM^-
• Gene: Tnfrsf14 Location: Chr4:155006390-155013020 bp, - strand Genetic Position: Chr4, 85.81 cM
• Alliance: Tnfrsf14^tm1Wwhk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:119356
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 3 through 6 were replaced with an IRES-GFP-neo cassette. The majority of the coding region contained in exons 3 through 10 is deleted. This allele is a null allele and a reporter allele. (J:134956)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnfrsf14 Mutation: 21 strains or lines available

References

• Original: J:119356 Tao R, et al., Differential effects of B and T lymphocyte attenuator and programmed death-1 on acceptance of partially versus fully MHC-mismatched cardiac allografts. J Immunol. 2005 Nov 1;175(9):5774-82
• All: 4 reference(s)