Ppp6c^tm1Shma
Targeted Allele Detail

Summary

• Symbol: Ppp6c^tm1Shma
• Name: protein phosphatase 6, catalytic subunit; targeted mutation 1, Hiroshi Shima
• MGI ID: MGI:5775125
• Synonyms: Ppp6c^flox
• Gene: Ppp6c Location: Chr2:39084381-39116361 bp, - strand Genetic Position: Chr2, 24.44 cM, cytoband B
• Alliance: Ppp6c^tm1Shma page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:231809
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• A neomycin resistance cassette was inserted downstream of a floxed exon 4. (J:231809)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Ppp6c^tm1Shma

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ppp6c Mutation: 40 strains or lines available

References

• Original: J:231809 Hayashi K, et al., Abrogation of protein phosphatase 6 promotes skin carcinogenesis induced by DMBA. Oncogene. 2015 Aug 27;34(35):4647-55
• All: 4 reference(s)