Trpv5^Hcalc1
Chemically induced Allele Detail

Summary

• Symbol: Trpv5^Hcalc1
• Name: transient receptor potential cation channel, subfamily V, member 5; hypercalciuria 1
• MGI ID: MGI:5501482
• Synonyms: Trpv5^682P
• Gene: Trpv5 Location: Chr6:41629107-41657703 bp, - strand Genetic Position: Chr6, 19.83 cM
• Alliance: Trpv5^Hcalc1 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to C transition in codon 682 that results in an amino acid substitution of proline for serine at position 682. (J:196612)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trpv5 Mutation: 49 strains or lines available

References

• Original: J:196612 Loh NY, et al., Autosomal dominant hypercalciuria in a mouse model due to a mutation of the epithelial calcium channel, TRPV5. PLoS One. 2013;8(1):e55412
• All: 1 reference(s)