Shld1^em1Nus
Endonuclease-mediated Allele Detail

Summary

• Symbol: Shld1^em1Nus
• Name: shieldin complex subunit 1; endonuclease-mediated mutation 1, Andre Nussenzweig
• MGI ID: MGI:6719506
• Gene: Shld1 Location: Chr2:132528871-132592975 bp, + strand Genetic Position: Chr2, 64.74 cM, cytoband F3
• Alliance: Shld1^em1Nus page

Mutation origin

• Strain of Origin: C57BL/6NCrl

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology targeting coding sequences 1 and 2 generated an approximate 250 bp deletion that includes part of coding sequence 1 and 2. (J:307190)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Shld1 Mutation: 78 strains or lines available

References

• Original: J:307190 Shinoda K, et al., The dystonia gene THAP1 controls DNA double-strand break repair choice. Mol Cell. 2021 Jun 17;81(12):2611-2624.e10
• All: 1 reference(s)