Rnf40^tm1.1Sajo
Targeted Allele Detail

Summary

• Symbol: Rnf40^tm1.1Sajo
• Name: ring finger protein 40; targeted mutation 1.1, Steven A Johnsen
• MGI ID: MGI:6781798
• Synonyms: Rnf40^loxP
• Gene: Rnf40 Location: Chr7:127187870-127202777 bp, + strand Genetic Position: Chr7, 69.61 cM
• Alliance: Rnf40^tm1.1Sajo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:311964
• Parent Cell Line: MPI-II (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 3 and 4 were flanked by loxP sites and an FRT-flanked neomycin selection cassette was also inserted. The neomycin cassette was removed via Flp-mediated recombination, leaving exons 3-4 floxed. (J:311964)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnf40 Mutation: 46 strains or lines available

References

• Original: J:311964 Xie W, et al., RNF40 regulates gene expression in an epigenetic context-dependent manner. Genome Biol. 2017 Feb 16;18(1):32
• All: 5 reference(s)