Cmklr1^tm1Drg
Targeted Allele Detail

Summary

• Symbol: Cmklr1^tm1Drg
• Name: chemerin chemokine-like receptor 1; targeted mutation 1, David R Greaves
• MGI ID: MGI:3785491
• Synonyms: ChemR23^-
• Gene: Cmklr1 Location: Chr5:113750415-113788487 bp, - strand Genetic Position: Chr5, 55.55 cM, cytoband F
• Alliance: Cmklr1^tm1Drg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:133968
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The majority of the coding region from 33 bp to beyond the translation stop codon was replaced with an IRES-lacZ cassette. This is a reporter and null allele as it lacks all but the first 12 amino acids of the protein. (J:133968)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cmklr1 Mutation: 46 strains or lines available

References

• Original: J:133968 Cash JL, et al., Synthetic chemerin-derived peptides suppress inflammation through ChemR23. J Exp Med. 2008 Apr 14;205(4):767-75
• All: 6 reference(s)