Tnip1^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Tnip1^m1Btlr
• Name: TNFAIP3 interacting protein 1; mutation 1, Bruce Beutler
• MGI ID: MGI:6200058
• Synonyms: trinity
• Gene: Tnip1 Location: Chr11:54801611-54853743 bp, - strand Genetic Position: Chr11, 32.13 cM
• Alliance: Tnip1^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 54,939,596 (v38) on chromosome 11, or base pair 23,345 in the GenBank genomic region NC_000077 within the donor splice site of intron 3. The effect of the mutation at the cDNA and protein levels have not examined, but the mutation is predicted to result in skipping of the 138-base pair exon 3. Skipping of exon 3 would result in an in-frame deletion of 46 amino acids beginning after amino acid 46 of the protein, which is normally 647 amino acids long. (J:265175)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnip1 Mutation: 55 strains or lines available

References

• Original: J:265175 Turer E, et al., Mutagenetix entry for trinity. MGI Direct Data Submission. 2018
• All: 1 reference(s)