Gt(ROSA)26Sor^tm1(Ntn4)Dyl
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm1(Ntn4)Dyl
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Dean Y Li
• MGI ID: MGI:4820644
• Synonyms: Rosa26^Netrin-4
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm1(Ntn4)Dyl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:162807
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^tm1(Ntn4)Dyl expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ntn4 (MGI:1888978)

• Mutation details: The mouse cDNA preceded by a floxed neo STOP cassette was inserted into the locus. Cre mediated recombination is required to remove the floxed neo STOP cassette to allow for expression of the cDNA. (J:162807)

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 942 strains or lines available

References

• Original: J:162807 Larrieu-Lahargue F, et al., Netrin-4 induces lymphangiogenesis in vivo. Blood. 2010 Jul 1;115(26):5418-26
• All: 1 reference(s)