Tg(HLA-B27)1Trg
Transgene Detail

Summary

• Symbol: Tg(HLA-B27)1Trg
• Name: transgene insertion 1, Joel D Taurog
• MGI ID: MGI:2159102
• Synonyms: line 56-3
• Transgene: Tg(HLA-B27)1Trg Location: unknown
• Alliance: Tg(HLA-B27)1Trg page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL/J)F2

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A transgene containing the human HLA-B allele, HLA-B27, was shown to be expressed in spleen cells of mice carrying the transgene. The HLA-B2705 and human B2M ( Tg(B2M)1Trg) constructs were co-injected and co-integrated. The line is designated 56-3. (J:74451)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:74451 Taurog JD, et al., HLA-B27 Transgenic Mice as Potential Models of Human Disease, in Transgenic Mice and Mutants in MHC Research. 1990:268-75.
• All: 1 reference(s)