Prkcd^M1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Prkcd^M1Btlr
• Name: protein kinase C, delta; mutation 1, Bruce Beutler
• MGI ID: MGI:6199962
• Synonyms: Rigged
• Gene: Prkcd Location: Chr14:30317311-30348167 bp, - strand Genetic Position: Chr14, 18.82 cM
• Alliance: Prkcd^M1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 30,610,301 (v38) on chromosome 14, or base pair 16,114 in the GenBank genomic region NC_000080 encoding Prkcd. The mutation corresponds to residue 10 in the mRNA sequence NM_001310682 within exon 1 of 17 total exons. The mutation results in a methionine to threonine substitution at position 1 (M1T) in the PRKCD protein. (J:265145)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkcd Mutation: 52 strains or lines available

References

• Original: J:265145 Turer E, et al., Mutagenetix entry for Rigged. MGI Direct Data Submission. 2018
• All: 1 reference(s)