Pgf^tm1Pec
Targeted Allele Detail

Summary

• Symbol: Pgf^tm1Pec
• Name: placental growth factor; targeted mutation 1, Peter Carmeliet
• MGI ID: MGI:2183459
• Synonyms: P1GF^-, Pgf^-, PIGF^-, Plgf-
• Gene: Pgf Location: Chr12:85213411-85224559 bp, - strand Genetic Position: Chr12, 39.58 cM, cytoband D
• Alliance: Pgf^tm1Pec page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:77481
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 3 through 6 were replaced by a neomycin selection cassette. (J:77481)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pgf Mutation: 14 strains or lines available

References

• Original: J:77481 Carmeliet P, et al., Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions. Nat Med. 2001 May;7(5):575-83
• All: 36 reference(s)