Ewsr1^tm1(ERG)Thr
Targeted Allele Detail

Summary

• Symbol: Ewsr1^tm1(ERG)Thr
• Name: Ewing sarcoma breakpoint region 1; targeted mutation 1, Terence H Rabbitts
• MGI ID: MGI:3584017
• Gene: Ewsr1 Location: Chr11:5019689-5049266 bp, - strand Genetic Position: Chr11, 3.22 cM, cytoband A1-A3
• Alliance: Ewsr1^tm1(ERG)Thr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:98679
• Parent Cell Line: CCB (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A targeting construct was designed to insert human ERG into the locus downstream of exon 7 and in reverse order of transcription, with expression dependent upon cre-mediated inversion of the cassette. (J:98679)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ewsr1 Mutation: 92 strains or lines available

References

• Original: J:98679 Forster A, et al., The invertor knock-in conditional chromosomal translocation mimic. Nat Methods. 2005 Jan;2(1):27-30
• All: 2 reference(s)