Zbtb17^tm1Cksn
Targeted Allele Detail

Summary

• Symbol: Zbtb17^tm1Cksn
• Name: zinc finger and BTB domain containing 17; targeted mutation 1, Christian Kosan
• MGI ID: MGI:3721142
• Synonyms: Miz-1^flox, Mizl^lox, Zbtb17^fldeltaneo
• Gene: Zbtb17 Location: Chr4:141171984-141195248 bp, + strand Genetic Position: Chr4, 74.17 cM, cytoband E1
• Alliance: Zbtb17^tm1Cksn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:123966
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 3 and 4, encoding the POZ/BTB domain, were flanked by loxP sites. A floxed neo cassette inserted downstream of exon 4 was removed by cre-mediated recombination. (J:123966, J:167721)

Expression

In Mice Carrying this Mutation:	52018 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Zbtb17 Mutation: 43 strains or lines available

References

• Original: J:123966 Gebhardt A, et al., Miz1 is required for hair follicle structure and hair morphogenesis. J Cell Sci. 2007 Aug 1;120(Pt 15):2586-93
• All: 12 reference(s)