Slc29a1^tm2Msg
Targeted Allele Detail

Summary

• Symbol: Slc29a1^tm2Msg
• Name: solute carrier family 29 (nucleoside transporters), member 1; targeted mutation 2, Robert O Messing
• MGI ID: MGI:5317195
• Synonyms: ENT1^flox
• Gene: Slc29a1 Location: Chr17:45896126-45910532 bp, - strand Genetic Position: Chr17, 22.59 cM, cytoband C
• Alliance: Slc29a1^tm2Msg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:92100
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct was designed to insert loxP sites flanking exons 2 through 4 followed by neomycin selection cassette and a third loxP site. Germ line, cre mediated recombination was used to remove the neomycin cassette, but retain the loxP flanked exons 2 through 4. (J:92100)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc29a1 Mutation: 40 strains or lines available

References

• Original: J:92100 Choi DS, et al., The type 1 equilibrative nucleoside transporter regulates ethanol intoxication and preference. Nat Neurosci. 2004 Aug;7(8):855-61
• All: 4 reference(s)