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Gene trapped Allele Detail
Symbol: Def6Gt(OST307148)Lex
Name: differentially expressed in FDCP 6; gene trap OST307148, Lexicon Genetics
MGI ID: MGI:3530790
Synonyms: Def6Gt(neo)551Lex, Def6trap, IBPtrap
Gene: Def6  Location: Chr17:28426752-28447582 bp, + strand  Genetic Position: Chr17, 14.64 cM
Alliance: Def6Gt(OST307148)Lex page
Mutant Cell Line:  OST307148
Germline Transmission:  Earliest citation of germline transmission: J:106469
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector
Mutation detailsA gene trap vector integrated into the first intron of the locus, downstream of the exon containing the ATG. Western blot failed to detect protein in mutants. (J:106469)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Def6 Mutation:  34 strains or lines available
Original:  J:106469 Fanzo JC, et al., Loss of IRF-4-binding protein leads to the spontaneous development of systemic autoimmunity. J Clin Invest. 2006 Mar;116(3):703-14
All:  20 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory