Clec5a^em1(IMPC)Mbp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Clec5a^em1(IMPC)Mbp
• Name: C-type lectin domain family 5, member a; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:7425593
• Gene: Clec5a Location: Chr6:40551832-40562739 bp, - strand Genetic Position: Chr6, 18.82 cM, cytoband B2
• Alliance: Clec5a^em1(IMPC)Mbp page
• IMPC: Clec5a gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at University of California, Davis using Cas9 and guides with spacer sequences GGAGATTAATGGCCCCTAAG and TCATACTCTAGGGACGTACC that targeted exon(s) ENSMUSE00000193772.4 ENSMUSE00000193776.4. This resulted in deletion(s) of 3 bp (location: Chr6:40558314-40558316; GRCm39), 154 bp (location: Chr6:40558468-40558621; GRCm39), and 928 bp (location: Chr6:40558627-40559554; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Clec5a Mutation: 19 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 4 reference(s)