Gzmbtm1Asmv
Targeted Allele Detail
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Symbol: |
Gzmbtm1Asmv |
Name: |
granzyme B; targeted mutation 1, Anne-Marie Schmitt-Verhulst |
MGI ID: |
MGI:5532521 |
Synonyms: |
Gzmb-tdTomato delta neo, Gzmbtm1.1Clbr, Gzmb-Tom-KI |
Gene: |
Gzmb Location: Chr14:56496295-56499717 bp, - strand Genetic Position: Chr14, 28.19 cM, cytoband D3
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Alliance: |
Gzmbtm1Asmv page
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Germline Transmission: |
Earliest citation of germline transmission:
J:203720
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Insertion of the tdTomato cDNA plus a 12 amino acid linker and a self-excising neomycin resistance cassette replaced the stop codon. A neomycin resistance cassette was deleted in ES cells prior to the creation of mice.
(J:203720)
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Generation of the Gzmbtm1Asmv allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gzmb Mutation: |
33 strains or lines available
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Original: |
J:203720 Mouchacca P, et al., Visualization of cytolytic T cell differentiation and granule exocytosis with T cells from mice expressing active fluorescent granzyme B. PLoS One. 2013;8(6):e67239 |
All: |
7 reference(s) |
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