Gata3^tm1Jml
Targeted Allele Detail

Summary

• Symbol: Gata3^tm1Jml
• Name: GATA binding protein 3; targeted mutation 1, Jeffrey M Leiden
• MGI ID: MGI:2153825
• Synonyms: GATA-3 -
• Gene: Gata3 Location: Chr2:9861889-9894845 bp, - strand Genetic Position: Chr2, 6.69 cM
• Alliance: Gata3^tm1Jml page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:37093
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A genomic fragment containing part of exons 4 and 5 was deleted and replaced with a neomycin resistance expression cassette. (J:37093)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gata3 Mutation: 31 strains or lines available

References

• Original: J:37093 Ting CN, et al., Transcription factor GATA-3 is required for development of the T-cell lineage. Nature. 1996 Dec 5;384(6608):474-8
• All: 1 reference(s)