Fat1^{Gt(KST249)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Fat1^{Gt(KST249)Byg}
• Name: FAT atypical cadherin 1; gene trap KST249, BayGenomics
• MGI ID: MGI:4124012
• Synonyms: Fat1^LacZ
• Gene: Fat1 Location: Chr8:45388484-45505294 bp, + strand Genetic Position: Chr8, 24.81 cM
• Alliance: Fat1^{Gt(KST249)Byg} page

Presymptomatic adult Fat1^{Gt(KST249)Byg}/Fat1^{Gt(KST249)Byg} Tg(Myl1-lacZ)1Ibdml/0 mice show selective defects in scapular muscles

Show the 9 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: KST249
• Germline Transmission: Earliest citation of germline transmission: J:199157
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1TMpfs Vector Type: secretory trap
• The gene trap vector inserted downstream of exon 1. This allele is hypomorphic.
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  KST249	CC144724 ; (MGI Seq Detail)	5' RACE	Chr8:45406374-45406509 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  63 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Schematic of the gene-trapped Fat1^{Gt(KST249)Byg} allele

Disease models

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fat1 Mutation: 208 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 5 reference(s)