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Phenotype Images associated with this Allele
Nomenclature
Symbol: Fat1Gt(KST249)Byg
Name: FAT atypical cadherin 1; gene trap KST249, BayGenomics
MGI ID: MGI:4124012
Synonyms: Fat1LacZ
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Presymptomatic adult Fat1Gt(KST249)Byg/Fat1Gt(KST249)Byg Tg(Myl1-lacZ)1Ibdml/0 mice show selective defects in scapular musclesFat1Gt(KST249)Byg/Fat1Gt(KST249)Byg
Tg(Myl1-lacZ)1Ibdml/0		involves: 129P2/OlaHsd
Reduction in volume and thickness of the rhomboid superficialis and rhomboid profundus muscles in Fat1Gt(KST249)Byg/Fat1Gt(KST249)Byg Tg(Myl1-lacZ)1Ibdml/0 miceFat1Gt(KST249)Byg/Fat1Gt(KST249)Byg
Tg(Myl1-lacZ)1Ibdml/0		involves: 129P2/OlaHsd
Muscle fibers from Fat1Gt(KST249)Byg/Fat1Gt(KST249)Byg Tg(Myl1-lacZ)1Ibdml/0 mice exhibit structural abnormalitiesFat1Gt(KST249)Byg/Fat1Gt(KST249)Byg
Tg(Myl1-lacZ)1Ibdml/0		involves: 129P2/OlaHsd
Fat1Gt(KST249)Byg/Fat1Gt(KST249)Byg Tg(Myl1-lacZ)1Ibdml/0 mice at early symptomatic stages show fragmentation of myofiber architecture and loss of t-tubule integrityFat1Gt(KST249)Byg/Fat1Gt(KST249)Byg
Tg(Myl1-lacZ)1Ibdml/0		involves: 129P2/OlaHsd
Retinal defects and exudative vasculopathy in adult Fat1Gt(KST249)Byg/Fat1Gt(KST249)Byg Tg(Myl1-lacZ)1Ibdml/0 retinasFat1Gt(KST249)Byg/Fat1Gt(KST249)Byg
Tg(Myl1-lacZ)1Ibdml/0		involves: 129P2/OlaHsd
Reduced endolymphatic duct and endolymphatic sac in E12.5 Fat1tm1.2Fhel/Fat1tm1.2Fhel Tg(Myl1-lacZ)1Ibdml/0 embryo inner earsFat1Gt(KST249)Byg/Fat1Gt(KST249)Byg
Tg(Myl1-lacZ)1Ibdml/0		involves: 129P2/OlaHsd
Fat1Gt(KST249)Byg/Fat1Gt(KST249)Byg Tg(Myl1-lacZ)1Ibdml/0 E12.5 embryos present dispersed myoblasts in ectopic positions in the shoulder areaFat1Gt(KST249)Byg/Fat1Gt(KST249)Byg
Tg(Myl1-lacZ)1Ibdml/0		involves: 129P2/OlaHsd
Muscle wasting in Fat1Gt(KST249)Byg/Fat1Gt(KST249)BygTg(Myl1-lacZ)1Ibdml/0 miceFat1Gt(KST249)Byg/Fat1Gt(KST249)Byg
Tg(Myl1-lacZ)1Ibdml/0		involves: 129P2/OlaHsd
Neuromuscular junction denervation and atrophy in Fat1Gt(KST249)Byg/Fat1Gt(KST249)Byg Tg(Myl1-lacZ)1Ibdml/0 miceFat1Gt(KST249)Byg/Fat1Gt(KST249)Byg
Tg(Myl1-lacZ)1Ibdml/0		involves: 129P2/OlaHsd
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory